Ibogaine is a natural psychoactive substance found in plants...

Ibogaine interrupts addiction safely and painlessly...

begin again, because YOU deserve freedom...

Science and History of Ibogaine

Twenty two years ago, we discovered an ancient natural tribal remedy in the Tabernanthe Iboga shrub native to Gabon and other nations in West Central Africa. This substance is called Ibogaine and it has an ancient history in shamanic rituals of initiation and spiritual quests.

In more recent times Ibogaine and its metabolite have shown a remarkable ability to interrupt various substance addictions. With the help of the ibogaine alkaloid, a natural hydrochloride extract, addicted individuals can experience symptom-free withdrawal.

Through the unique binding activity of the metabolite, Ibogaine offers a full physiological release from chemical dependency.

Ibogaine is a psychoactive substance that interrupts addiction by neurochemically transporting the addict to a physically and psychologically pre-addicted state.

Individuals can then evaluate their habits from the standpoint of a non-addict without having to suffer through any terrifying withdrawal symptoms.

To heal the psychological aspects of addiction, the underlying causes, we recommend a specific form of psychotherapy following our ibogaine treatments.

Ibogaine-Methadone Treatment Protocols:

There are different schools of thought regarding methods and protocols for treating opioid compounds. Ibogaine-Suboxone (buprenorphine) therapy has been widely misunderstood and continues to be a controversy due to clinics offering various forms of treatment for users of Suboxone and other opioid replacement therapies. There are many ways to treat suboxone addictions, however, there are a few universal rules that apply to all users of buprenorphine medications.

Thanks to the combined knowledge of Eric Taub and Lex Kogan, I Begin Again’s treatment center offers the most straightforward instructions on Suboxone and Ibogaine preparation methods. Ibogaine-Methadone treatment protocols are also customized for the individual and these clients receive a full medical review prior to being evaluated as a candidate for an Ibogaine therapy session.

How Ibogaine Works:

There has been renewed interest in studying ibogaine over the past several decades due to the experienced effect that ibogaine has during withdrawing from drug addiction. It has been proven in pre-clinical trials to reduce self-administration of cocaine, morphine, and amphetamines.

It is believed that Ibogaine will break the pattern of addiction, whether the addiction in question is physical or emotional. Ibogaine is also further believed to provide insight and guidance into a person’s life. Ibogaine is said to act on the mammalian GDNF or addiction pathway.

New Research:

Recent studies have shown that ibogaine – and its primary metabolite – interact with numerous neuro-receptors and neuro-transporters. These make up the cellular network that modulates the activity of dopaminergic-dependent (related to the neurotransmitter dopamine) and independent circuits. The multi-site actions of ibogaine suggest that simultaneous modulation of more than one neural mechanism may therefore be an effective pharmacological treatment approach.

The action of the Ibogaine seems to reduce dopamine concentrations in the body. This is proven by the presence of dopamine metabolites – dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) – in increased amounts after ibogaine administration. This action of Ibogaine is what seems to reverse the affects of certain abusive and highly addictive drugs, namely/specifically: cocaine, morphine, amphetamines and nicotine. All of these drugs act upon dopaminergic systems thus stimulating dopamine production in the body. Ibogaine seems to reverse this process by antagonizing dopaminergic systems.

Ibogaine is also thought to reduce addiction because it inhibits naloxone (used in overdose of opiates to counteract life-threatening depression of the central nervous and respiratory systems), precipitating the blockade of NMDA channels (the predominant molecular device for controlling synaptic plasticity and memory function). Ibogaine can readily affect serotonergic (related to the neurotransmitter serotonin) transmission in the brain, as this has been observed in clinical studies. But once again the mechanisms of action on the many serotonergic receptors are complex and not completely understood.

Most interestingly, Ibogaine is proven to inhibit self-administration of cocaine in rats. In fact, one dose of Ibogaine would decrease cocaine consumption in 5 days by 60-80%. Ibogaine was also found to lower the self-administration of morphine and alcohol. Psychologically, Ibogaine is capable of producing visions and hallucinations at high doses. Some common questions about this are addressed on this site’s FAQ.

It has been established that Ibogaine affects the central nervous system in a variety of ways. Many studies have been conducted regarding the behavioral effects of Ibogaine on drug-dependent patients. Ibogaine has been found to produce no significant neurobehavioral impairments. Acute effects include mild tremors and a dramatic resurgence of repressed memories. These visions sometimes lasted up to 8 hours and eventually subsided into a 24-hour state of relaxation. Some patients also experience mild insomnia after the treatment, but this has not affected their sensorium (sensations).

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